CZRC Catalog ID: |
CZ1219 |
Availability: |
Frozen sperm |
Genotype: |
tnfrsf1aihb319/+ |
Affected Gene: |
tnfrsf1a |
Genotyping: |
pdf |
Background: |
AB |
Affectedgeneurl: |
unspecified |
Linetype: |
Mutant |
Previous Names: |
TNFR1 (1), TNF Receptor 1 (TR1) (1), wu:fj65b10, zgc:85914 |
Background: |
AB |
Affectedgeneurl: |
unspecified |
Linetype: |
Mutant |
Previous Names: |
TNFR1 (1), TNF Receptor 1 (TR1) (1), wu:fj65b10, zgc:85914 |
Note:
Predicted to have tumor necrosis factor binding activity and tumor necrosis factor-activated receptor activity. Involved in several processes, including defense response to other organism; fin regeneration; and neutrophil chemotaxis. Predicted to localize to the membrane raft; mitochondrion; and receptor complex. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; Legionnaires' disease; acne; allergic bronchopulmonary aspergillosis; and autosomal dominant familial periodic fever. Orthologous to human TNFRSF1A (TNF receptor superfamily member 1A).
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