| CZRC Catalog ID: |
CZ272 |
| Availability: |
Frozen sperm |
| Genotype: |
topbp1cas003/+ |
| Affected Gene: |
topbp1 |
| Genotyping: |
pdf |
GENOTYPE COMPOSITION
| Genomic Feature |
Zygosity |
Parental Genotype |
Lab of Origin |
Construct |
|---|
| cas003 |
heterozygous |
|
Weijun Pan Lab |
|
| Background: |
AB |
| Affectedgeneurl: |
https://zfin.org/ZDB-GENE-060626-1 |
| Linetype: |
Mutant |
| Previous Names: |
unspecified |
| Background: |
AB |
| Affectedgeneurl: |
https://zfin.org/ZDB-GENE-060626-1 |
| Linetype: |
Mutant |
| Previous Names: |
unspecified |
Note:
| C to T nonsense mutation in topbp1 gene causing an earlier stop codon before the eighth BRCT (BRCA1 C-terminus) domain and a putative C-terminus nuclear localization signal (NLS) of TopBP1 protein
|
